Low growth hormone - Vivo Health

What is Low Growth Hormone?

Growth hormone (GH), also known as somatotropin, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration. It is secreted by the anterior pituitary gland in the brain. Low growth hormone, or growth hormone deficiency (GHD), is a clinical syndrome caused by inadequate production of GH.

Signs and Symptoms

During childhood, signs and symptoms of low GH typically include:

• Short stature and poor growth
• Delayed sexual development
• Increased body fat, especially around the waist
• Low muscle strength and tone
• Anxiety, irritability, social isolation
• Delayed tooth development
• Lower energy levels and endurance

During adulthood, symptoms may include:

• Decreased muscle mass and strength
• Weight gain, high cholesterol
• Reduced physical and mental endurance
• Decreased bone density (osteoporosis risk)
• Impaired heart function
• Low libido

Causes

GHD can be caused by:

• Congenital - Genetic mutations and developmental pituitary abnormalities
• Acquired later in life due to:
  • Pituitary tumors
  • Inflammation/infection
  • Brain surgery or radiation
  • Traumatic brain injury
  • Certain autoimmune disorders

Diagnosis and Treatment

Diagnosis involves analysis of GH and IGF-I (insulin-like growth factor) blood levels combined with stimulation testing to assess the pituitary's capacity to produce adequate GH.

Treatment with FDA-approved synthetic growth hormone injections can help normalize height in children and reverse many hormonal and metabolic abnormalities in both children and adults. Early treatment leads to better outcomes.

Monitoring hormone levels and long-term side effects are an important part of treatment. Adherence to the prescribed regimen allows GH replacement to effectively manage symptoms, bolster wellbeing, and help patients realize their full growth and health potential. Consult an endocrinologist at Vivo Health to determine if treatment is appropriate.